Clinical features and neuropsychiatric comorbidities in pediatric patients with tic disorders: a retrospective chart review study from South Korea

Abstract Background Tic disorders are childhood-onset neuropsychiatric characterized by multiple motor or vocal tics with frequent comorbidities and a broad spectrum of phenotypic presentations. In this study, we aimed to investigate the clinical characteristics comorbid conditions in pediatric patients tic disorders. Methods We retrospectively reviewed medical records 119 (89 males, 30 females) who were diagnosed according Diagnostic Statistical Manual Mental Disorders, 5th edition (DSM-5) at Uijeongbu St. Mary’s Hospital, Republic Korea, between January 2012 July 2019. Results The mean age onset was 6.9 years (range, 1–14) diagnosis 8 1–17). lag 13.3 months 0.25–132). most common, first-presenting eye blinking (50.4%), followed jaw lip movement (29.4%) throat clearing (29.4%). Thirty-seven (31.1%) had least one co-occurring disorder time diagnosis. Subtypes disorders, types initial tics, presence not associated severity. severity greater functional impairment noticeability ( p < 0.05). A relatively shorter (Spearman’s ? = ? 0.14, 0.11). Conclusions evolving nature expression severity, high prevalence comorbidities, impairments emphasize importance comprehensive assessment during disease course for determining prioritizing goals treatment.